A data-driven nutrition framework built on high-fat, high-protein diets and emerging peptide research. Designed for those who refuse to accept average.
Mainstream nutrition has been dominated by carbohydrate-centric models for decades. The evidence is shifting. High-fat, high-protein diets are being rediscovered not just for weight management, but for cognitive clarity, hormonal optimisation, and longevity.
PeakOPTI synthesises cutting-edge metabolic research with animal-based nutritional frameworks you can actually implement — whether you're a student juggling deadlines, or someone investing seriously in long-term performance.
Train your body to efficiently burn both fat and glucose. Reduce energy crashes and sustain deep focus for hours.
Dietary fats are precursors to key hormones. Restriction leads to decline. Sufficiency leads to optimisation.
Every recommendation is cross-referenced against peer-reviewed data. We cite our sources — always.
Short-term gains matter less than compounding returns. Our protocol is built for a lifetime of performance.
Three core pillars. Each backed by research. Each built to compound on the others.
The macro hierarchy, animal food ranking, and the evidence against seed oils. Learn how to structure fat, protein, and carbohydrate intake for maximal metabolic output.
→ Explore NutritionFrom BPC-157 to MOTS-c, explore the frontier of research-grade compounds being studied for tissue regeneration, body recomposition, and longevity signalling.
→ Explore PeptidesKetone cognition, mitochondrial density, anabolic environment, sleep architecture. The six biological pathways that explain why this protocol works.
→ Explore ScienceAnimal foods are the most nutrient-dense substances available to the human body — and the only category of food that delivers every essential nutrient in a form the body can fully absorb and utilise. Meat, organs, eggs, and fatty fish provide complete amino acid profiles, fat-soluble vitamins in their active forms, and compounds — creatine, carnosine, taurine, haem iron, EPA, DHA, choline — that are either absent or biologically insignificant in plant sources. This is not a dietary preference. It is a question of biochemistry.
Organ meats — particularly beef liver — are the single most micronutrient-dense food that exists. A 100g serving of liver delivers more retinol, B12, copper, folate, and CoQ10 than any plant food by an order of magnitude. Fatty fish provide EPA and DHA directly in their pre-formed state, critical for brain structure, neurological function, and systemic inflammation control. Whole eggs — four to six daily — deliver phospholipid-bound DHA, choline for neurotransmitter synthesis, and a complete fat-soluble vitamin matrix in a single food. These are the foods that build hormones, sustain lean mass, and fuel cognitive performance. Build every meal around them.
Red meat from ruminant animals — beef, lamb, bison, venison — provides the highest concentrations of leucine for muscle protein synthesis, alongside zinc, creatine, and carnosine that have no plant equivalent. Saturated animal fat from butter, tallow, and ghee is chemically stable, resistant to oxidation, and the primary structural substrate for every cell membrane and steroid hormone in the body. This is the nutritional foundation that humans evolved on — and the one the body still functions best with.
With that foundation established, the case against non-animal foods becomes straightforward. Grains deliver energy at the cost of insulin spikes, gut disruption, and phytic acid that chelates the very minerals they claim to provide. Fruit is a concentrated fructose delivery mechanism — processed directly by the liver, converted to triglycerides in excess, and incapable of signalling satiety. Vegetables, though culturally revered, are frequently counterproductive: oxalates in leafy greens bind calcium and iron, glucosinolates in cruciferous vegetables suppress thyroid function, and the micronutrients they do contain require fat for absorption and are present in far superior concentrations in animal tissue. None of these foods are necessary. They are at best neutral additions to an already complete animal-food protocol — and at worst, active impediments to it.
Fat and protein aren't the enemy — they are the foundation. Here's how we structure intake for maximal output.
Fat is the most energy-dense macronutrient at 9 kcal/g — more than double that of carbohydrates or protein. Contrary to decades of flawed epidemiology, dietary fat does not cause obesity or cardiovascular disease in isolation. The demonisation of saturated fat was built on cherry-picked data and industry-funded misrepresentation. Animal fats are the original human fuel.
Saturated animal fats — butter, ghee, beef tallow, lamb fat, duck fat, lard — are chemically stable, highly resistant to oxidation, and serve as the direct structural backbone of every cell membrane. They are the primary substrate for steroid hormone synthesis including testosterone, cortisol, and DHEA. Omega-3 fats from wild salmon, sardines, mackerel, and herring deliver EPA and DHA directly in their most bioavailable form — DHA is the dominant structural fat in brain grey matter and retinal tissue. Egg yolk fat is uniquely dense in phospholipid-bound DHA, choline, and fat-soluble vitamins A, D, E, and K2. Avoid all industrial seed oils — they are high in oxidised omega-6 and mechanistically linked to systemic inflammation and mitochondrial dysfunction.
Protein is the literal building material of every structural and functional system in the body — enzymes, hormones, antibodies, contractile muscle fibres, and neurotransmitter precursors are all constructed from amino acids. Insufficient intake doesn't just impair performance; it accelerates biological ageing. Only animal-derived protein delivers the complete amino acid profile in the ratios and bioavailability the human body actually requires.
Red meat — beef, lamb, venison, bison — provides the highest leucine concentrations for mTOR-mediated muscle protein synthesis, alongside haem iron, zinc, creatine, carnosine, and taurine. Organ meats, particularly beef liver, are the single most nutrient-dense food on earth: 100g delivers ~27g protein, full B12 RDA, retinol, copper, folate, CoQ10, and choline. Whole eggs have a biological value of ~100 — the highest of any whole food — with the yolk delivering phospholipid-bound DHA and fat-soluble vitamins. Target 4–6 whole eggs daily, organ meats 2–3× weekly, and fatty fish 3–5× weekly as protocol minimums.
Carbohydrates are the only non-essential macronutrient. The human body has no biological requirement for dietary carbohydrates — glucose can be synthesised endogenously via gluconeogenesis from protein and fat substrates. That does not mean carbs are forbidden, but their role is narrow and strictly context-dependent.
If used at all, restrict strictly to the post-training window, where elevated insulin sensitivity partitions glucose toward muscle glycogen rather than adipose tissue. Many fully fat-adapted individuals perform and recover just as well — or better — with zero dietary carbohydrates, relying entirely on gluconeogenesis. Eliminate all processed grains, refined sugars, and ultra-processed carbohydrate products unconditionally — these provide zero nutritional value and actively disrupt metabolic signalling.
Not all animal foods are equivalent. Here's how we rank them by nutritional density, fat quality, and overall protocol impact.
Beef liver, kidney, heart, and brain. The most nutrient-dense foods in existence. Liver alone covers B12, retinol, copper, folate, CoQ10, and choline in a single 100g serving. Consume 2–3× weekly minimum.
Biological value of ~100 — the highest of any whole food. The yolk delivers phospholipid-bound DHA, choline, fat-soluble vitamins A, D, E, and K2, and a complete amino acid matrix. 4–6 whole eggs daily is the PeakOPTI baseline.
Wild salmon, mackerel, sardines, herring, and anchovies. Unrivalled EPA + DHA delivery alongside complete protein. The anti-inflammatory and neurological benefits are immediate and measurable. Target 3–5 servings weekly.
Ribeye, brisket, lamb shoulder, 80/20 minced beef, venison. Prioritise fattier cuts for combined protein and animal fat delivery. Dense in haem iron, zinc, creatine, carnosine, and fully bioavailable B vitamins.
Chicken thighs, duck breast, turkey legs. Prefer dark meat for fat content. Bone broth from carcasses provides glycine, proline, and collagen precursors for connective tissue and gut lining integrity that muscle meat alone cannot supply.
Butter, ghee, beef tallow, duck fat, lard. Every meal cooked exclusively in animal fat. Structurally stable at high temperatures — unlike seed oils which oxidise and form toxic aldehyde byproducts when heated above their smoke point.
Aged cheese, cream, and full-fat Greek yoghurt from grass-fed sources. High in CLA, vitamin K2, and fat-soluble vitamins. Valuable for those without intolerance. Avoid all skimmed or low-fat dairy variants.
Canola, soybean, sunflower, corn, cottonseed, rapeseed. Industrially extracted, loaded with unstable omega-6, and oxidise rapidly during cooking into toxic aldehydes. Mechanistically linked to systemic inflammation, metabolic dysfunction, and mitochondrial damage.
A peptide is a short chain of amino acids found naturally occurring within the human body. A peptide can be used systemically through subcutaneous injections into body fat to signal to your body's natural receptors to perform a task. Peptides can be used for the brain, skin, metabolism, hormones, muscles and many other areas of physiology.
Peptides are often administered through injections because they work systemically — far more effective than a pill, powder or topical product. This is because they provide rapid, total-body treatment that bypasses the limitations of the digestive system and skin barrier. The result is direct bioavailability at the cellular level.
Peptides have been around for a long time but are often frowned upon for not being "FDA approved" — which is largely irrelevant. FDA approval does not correlate with higher or lower health risk. The FDA has documented financial ties and incentives with sponsoring pharmaceutical companies, meaning industry money is deeply entangled with which products receive approval. This is a regulatory capture problem, not a safety endorsement.
Peptides have not been fully trialled and remain unapproved partly because they are far more complex than a simple pill. Only peptides with major commercial upside — like GLP-1 agonists (Ozempic) — receive approval because they can be mass-produced and sold at scale. Many peptides require careful biological synthesis to correctly format molecules and amino acid sequences, making them commercially unattractive to large pharmaceutical companies.
It is expected that many peptides will never receive formal approval, meaning published human trials may never be undertaken. This can make peptides appear "unsafe" by default. However, with correct biological synthesis and sourcing, a peptide can greatly enhance quality of life for individuals who struggle with sleep, libido, skin health, weight loss, insulin sensitivity, and more — problems that may be inherently genetic or simply resistant to diet alone.
Every peptide featured in this index is sourced exclusively through biological synthesis — the only method capable of producing correctly formatted amino acid sequences that match endogenous human peptides. PeakOPTI maintains a minimum 99% purity threshold across all compounds, verified by third-party HPLC testing. We do not source from chemical synthesis operations or unverified suppliers. Quality of synthesis is the single most important variable in peptide safety and efficacy — and it is non-negotiable.
The most researched healing combination in performance science. BPC-157 drives structural repair at the local tissue level — targeting tendons, ligaments, gut mucosa, and nitric oxide-mediated angiogenesis. TB-500 (Thymosin Beta-4) operates systemically, regulating actin polymerisation and accelerating cell migration to injury sites. Together they create a compounding regenerative effect: localised repair amplified by systemic cellular signalling. Animal model data shows unusually rapid musculoskeletal tissue remodelling with this combination.
A naturally occurring plasma tripeptide (glycine-histidine-lysine) bound to copper, abundant in youth and declining sharply with age — from ~200ng/mL at 20 to under 80ng/mL by 60. GHK-Cu has been shown to modulate over 4,000 human genes: upregulating tissue repair and metabolic health pathways while downregulating inflammatory and oncogenic ones. It supports collagen and elastin synthesis, anti-oxidative gene expression, and DNA repair — representing one of the few peptides with documented systemic anti-ageing effects at the gene regulation level.
CJC-1295 extends endogenous GH pulse half-life through DAC technology, binding albumin to sustain active stimulation for days rather than minutes. Ipamorelin is a selective GHRP that mimics ghrelin at the pituitary without the cortisol or prolactin elevation seen in older GHRPs. Combined, they act on two distinct receptor pathways simultaneously — producing synergistic GH release that mirrors youthful pulsatile physiology. Research applications include lean mass preservation, accelerated fat metabolism, improved sleep architecture, and enhanced recovery.
A first-in-class GLP-1 / GIP / glucagon triple agonist. Phase II data (2023) showed up to 24% body weight reduction over 48 weeks. GLP-1 suppresses appetite; GIP improves nutrient partitioning; glucagon elevates energy expenditure and drives hepatic fat clearance. For body recomposition — fat loss with muscle retention — a conservative low-dose protocol is favoured: 0.5mg weekly (weeks 1–4) for tolerance establishment, escalating to 1–2mg weekly (weeks 5–12) for active recomposition. Pair with 2.2g+ protein per kg bodyweight and resistance training 3–5× weekly to protect lean mass via mTOR signalling.
One of the most extraordinary recent discoveries in peptide science — encoded not by the nuclear genome but by the mitochondrial genome itself. First identified at USC in 2015, MOTS-c is secreted by mitochondria under metabolic stress and functions as a retrograde hormonal signal, travelling to the nucleus to regulate gene expression and systemic metabolism. It activates AMPK — the master cellular energy sensor — and upregulates GLUT4-independent glucose uptake in skeletal muscle, improving insulin sensitivity without insulin involvement. In animal studies, MOTS-c has reversed diet-induced obesity and age-related metabolic decline. Circulating levels decline significantly with age. Combined with an animal-fat-dominant diet, MOTS-c may enhance mitochondrial adaptation to fat oxidation and accelerate the transition to full metabolic flexibility — signalling from the cell's energy centre outward to systemic tissue and gene networks.
High-fat, high-protein nutritional frameworks may create a particularly conducive environment for peptide research protocols. Dietary fat provides the lipid substrate necessary for cell membrane fluidity — which affects receptor sensitivity. Protein sufficiency ensures amino acid availability for endogenous peptide synthesis. The emerging hypothesis: that optimal macronutrient intake may potentiate the effects observed in peptide studies, while also reducing the anabolic resistance seen in suboptimal nutritional states. This is an active and exciting area of investigation at the intersection of nutritional biochemistry and peptide pharmacology.
Six biological pathways that explain the protocol at a molecular level — from mitochondrial function to hormonal architecture.
Beta-hydroxybutyrate is a preferred substrate for the brain, crossing the blood-brain barrier more efficiently than glucose in certain states. Sustained fat oxidation supports neurological energy without glycaemic volatility.
High-fat diets combined with strategic training protocols are associated with improvements in mitochondrial biogenesis via PGC-1α upregulation — the master regulator of energy metabolism.
Adequate dietary cholesterol and saturated fat intake supports testosterone and other anabolic hormone production. Chronic fat restriction is associated with measurable declines in reproductive hormone profiles.
Protein and fat-dominant pre-sleep nutrition has been associated with improved slow-wave sleep duration and GH pulse amplitude — both critical for physical and cognitive restoration.
EPA and DHA omega-3 fatty acids from fatty fish and egg yolks modulate the NF-κB inflammatory pathway and competitively displace pro-inflammatory omega-6 from cell membranes. Animal-derived omega-3s are immediately bioavailable — unlike ALA from plant sources, which converts to EPA/DHA at less than 5% efficiency in humans.
Animal protein preserves lean mass during caloric restriction through elevated thermic effect (~30% of calories burned in digestion), superior leucine content for mTOR activation, and creatine and carnosine — compounds exclusive to animal tissue that directly enhance intramuscular energy buffering and muscular endurance.